An irate driver was arrested Monday night in Northern England after driving his car through a crowd of Liverpool supporters celebrating their Premier League title triumph.

The small family-sized car ploughed into the crowd of Liverpool fans, instantly hospitalising 27 people, with two seriously injured, but police said they did not believe the incident was terrorism-related.

Police said they had arrested a "53-year-old white British man from the Liverpool area," whom they believed to be the driver of the vehicle which struck a large group of supporters who were celebrating in the city in northwest England.

Videos on social media seen by Radio Generation Sport showed people thrown into the air as the car rammed into spectators.

There were no reports of fatalities yet.

When the car stopped, angry fans converged on it and began smashing the windows as police officers intervened to prevent them from reaching the driver.

Police managed to keep the fans away and secured the man, whose identity was yet to be released.

"We believe this to be an isolated incident, and we are not currently looking for anyone else in relation to it. The incident is not being treated as terrorism," temporary Deputy Chief Constable Jenny Sims told reporters.

With most people off work for the Spring Bank Holiday, hundreds of thousands of fans gathered to watch the Liverpool team and its staff travel through the city centre on an open-top bus with the Premier League trophy.

Liverpool clinched their 20th overall English League title over the weekend, finishing the season with 84 points, leaving second-place Arsenal ten points behind in Dutch manager Arne Slot's first season in charge.